Using genetics to reconstruct the peopling and diversification of Sahul

Start date
End date
Research partner(s)
University of Adelaide

A recent landmark study has revealed that people who first arrived on Sahul (the landmass connecting Australia with New Guinea) remained largely genetically isolated from subsequent migrations. However, there is still little known about the route(s) taken into Sahul, or how adaptation has shaped the enormous diversity now observed across Indigenous Australians and Papuans. This project aims to look at these issues by applying phylogenetic and population genetic tools to the largest genetic dataset yet analysed from populations across Australia, New Guinea, and Island South East Asia. The outcomes of the project should reveal both the route(s) taken into Sahul and how adaptation has shaped the diversity now observed in descendants of the colonisation.

Output(s)

Binding affinities of 438 HLA proteins to complete proteomes of seven pandemic viruses and distributions of strongest and weakest HLA peptide binders in populations worldwide
Type
Journal article
Authors
Barquera, R., Collen, E., Di, D., Buhler, S., Teixeira, J., Llamas, B., Nunes, J. M., & Sanchez-Mazas, A.
Publisher
HLA
Publication date
Rights notice
Copyright © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.